Endocrine Abstracts

Introduction: Rathke cleft cysts (RCC) are benign cystic lesions of the sellar and suprasellar region, which is believed to arise from the remnants of the Rathke pouch. Symptomatic RCC are rare. Endocrine symptoms are usually caused by compression of the surrounding pituitarygland. It can therefore cause hypopituitarism, but it is rarely associated with primary endocrine dysfunctions. In this case, we report a co-occurrence of premature ovarian insufficiency and RCC.<p cla...

Introduction: Diabetic foot disease is a major health problem. The identification of its risk factors should guide preventive measures. The aim of this study was to determine the factors associated with diabetic foot complications.Patients and methods: It is a retrospective study including 47 patients admitted at the department of Endocrinology in La Rabta hospital for diabetic foot complications during the years 2015 and 2016. Clinical and para-clinical...

Recently, special attention has been paid to the relationship between doctors and the pharmaceutical industry. The aim of this work was to evaluate the attitude of Tunisian endocrinologists towards pharmaceutical promotion.Methods: It was a cross-sectional study based on an anonymous 9-item survey about the attitudes and behaviors of physicians towards the pharmaceutical promotion. The study included 120 participants.Results: One-t...

Introduction: Ganglioneuromas (GN) are rare benign tumors arising from the neural crest tissue and are most commonly located in the posterior mediastinum and retroperitoneum; they are rarely found in the adrenal gland. We report a case of a female patient with adrenal ganglioneuroma.Observation: A 51-year-old female patient with no previous comorbidities was admitted to our hospital. She had no significant past medical or surgical history. She had sympto...

IntroductionCerebral tuberculomas are a rare form of tuberculosis due to the hematogenous spread of Mycobacterium Tuberculosis (MT). Pituitary localization is exceptionally uncommon with total reported cases in the literature fewer than a hundred. Symptoms and radiologic features are nonspecific, leading sometimes to misdiagnosis. We report the rare case of a patient diagnosed with a primary pituitary stalk tuberculosis.Observation...

Introduction Growth hormone (GH ) deficiency is a rare but not exceptional cause of statural delay in children. The results of GH stimulation tests and the exploration of other pituitary axes allow us to conclude on the nature of the deficiency: total or partial and its possible association with other pituitary deficits.MethodsThis is a retrospective descriptive study including 75 patients followed for congen...

IntroductionHematological abnormalities are frequently observed in hyperthyroidism and are part of complex, multifactorial pathogenetic mechanisms that are still poorly understood, which can affect the three hematopoietic lineages in isolation or in combination. For the endocrinologist, they raise the issue of the risk of their aggravation under the hamatotoxic effect of antithyroid drugs (ATDs).Case presentation<p class="abste...

IntroductionGrowth hormone deficiency (GHD) is a rare cause of statural retardation in children. The diagnosis is evoked in front of a bundle of anamnestic, clinical and radiological arguments. Treatment consists of substitution by recombinant GH with the aim of restoring normal size. There is interindividual variability in the response to treatment. We therefore proposed to study the response to treatment as well as the predictive factors of this respon...

IntroductionCongenital GH deficiency is more common in boys than in girls. Several differences have been noted between the 2 genders. We proposed to study these differences for epidemiological, auxological and anthropometric characteristics.MethodsThis is a retrospective study including 75 patients followed for congenital GH deficiency in the endocrinology department at the National Institute of Nutrition in ...

IntroductionRathke Cleft Cysts (RCC) are common benign cystic lesions in the sellar region. These cysts are often small, intrapituitary and asymptomatic. Voluminous forms are rare and can be symptomatic by compressing the adjacent structures. We report the case of pituitary insufficiency related to RCC.ObservationA male patient aged 49 years old, diagnosed with type 2 diabetes since 8 years treated with metfo...